grant

A Comprehensive Resource for Manipulating and Characterizing the Drosophila Genome

Organization BAYLOR COLLEGE OF MEDICINELocation HOUSTON, UNITED STATESPosted 1 Jul 2021Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY202521+ years oldAbscissionAdultAdult HumanAllelesAllelomorphsAntibodiesBiologicalBody TissuesBrainBrain Nervous SystemBypassCRISPRCRISPR/Cas systemCell BodyCell Communication and SignalingCell FunctionCell PhysiologyCell ProcessCell SignalingCellsCellular FunctionCellular PhysiologyCellular ProcessChromosomesClustered Regularly Interspaced Short Palindromic RepeatsCodeCoding SystemCollectionCommunitiesDNA Insertion ElementsDNA Transposable ElementsDNA cassetteDataDepositDepositionDetectionDiseaseDisorderDrosophilaDrosophila genomeDrosophila genusEncephalonEnhancersExcisionExonsExpression SignatureExtirpationFat BodyFemaleFliesFoundationsGametesGene CombinationsGene ExpressionGene Expression ProfileGene Transfer TechniquesGeneHomologGenerationsGenesGeneticGenetic MarkersGerm CellsGerm-Line CellsGliaGlial CellsGrantGuide RNAHomologHomologous GeneHomologueHumanHuman GeneticsImageIndividualInternationalIntervening SequencesIntracellular Communication and SignalingIntronsInvestigatorsKolliker's reticulumLaboratoriesLarvaLettersLibrariesLightMapsMediatingMedicineMethodsMicroscopyMissionModern ManMuscle CellsMyocytesNerve CellsNerve UnitNervous SystemNeural CellNeurocyteNeurogliaNeuroglial CellsNeurologic Body SystemNeurologic Organ SystemNeuronsNon-neuronal cellNonneuronal cellOrthologOrthologous GeneOther GeneticsPatternPhenotypePhotoradiationPhotoreceptor CellPhotoreceptorsPhotosensitive CellProteinsReagentRemovalReporterReproductive CellsResearchResearch PersonnelResearch ResourcesResearchersResourcesRoleSex CellSignal TransductionSignal Transduction SystemsSignalingSiteSomatic CellSubcellular ProcessSurgical RemovalTechnologyTimeTissuesTransgenesisTransgenic OrganismsTransposable ElementsVariantVariationVisual Receptoradulthoodarmbiologicbiological signal transductioncell typecollegecollegiatedesigndesigningempowermentenhancer cassetteexperimentexperimental researchexperimental studyexperimentsexpression cassetteflyfruit flyfruit fly genomefunctional genomicsgRNAgene biomarkergene cassettegene conservationgene expression biomarkergene expression patterngene expression signaturegene functiongene markergene signature biomarkergenetic biomarkergenetic cassettegenetic strainhomologous recombinationimage-based methodimagingimaging methodimaging modalityin vivoinitial cellinsertion elementinsertion sequenceintegration cassetteloss of functionmalenerve cementneuronalnoveloverexpressoverexpressionpromoterpromoter cassettepromotorpublic data basepublic databasepublicly accessible data basepublicly accessible databasepublicly available data basepublicly available databaserecombinasereconstitutereconstitutionreporter cassetteresectionresistance cassetteselectable cassetteselection cassettesexual cellsocial rolespatial and temporalspatial temporalspatiotemporalstop cassettetooltranscription cassettetranscriptional cassettetranscriptional profiletranscriptional signaturetransgene cassettetransgenicweb sitewebsite
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PROJECT SUMMARY
The Drosophila Gene Disruption Project (GDP), since its inception, has produced a large, publicly available

library of individual, sequence-mapped transposable element (TE) insertions that have become an

essential resource for fly research. More than 1,000,000 GDP fly cultures have been distributed to

thousands of labs nationally…

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A Comprehensive Resource for Manipulating and Characterizing the Drosophila Genome — BAYLOR COLLEGE OF MEDICINE | UNITED | Dev Procure