grant
1/2 CORD-CHD: Clamp OR Delay among neonates with Congenital Heart Disease
Organization RESEARCH INST NATIONWIDE CHILDREN'S HOSPLocation COLUMBUS, UNITED STATESPosted 1 Apr 2023Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY20250-11 years old0-4 weeks oldACOGAbdominal DeliveryAcademyAgeAmericanAmerican College of Obstetricians and GynecologistsAmerican College of Obstetricians and GynecologyAmerican College of Obstetrics and GynecologistsAmerican College of Obstetrics and GynecologyAnatomic SitesAnatomic structuresAnatomyApoplexyBirthBirth DefectsBloodBlood Reticuloendothelial SystemBody SystemBrain Vascular AccidentC sectionCardiac CatheterizationCardiac Catheterization ProceduresCardiac MalformationCardiac SurgeryCardiac Surgery proceduresCardiac defectCatheterizationCells Placenta-TissueCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCesareanCesarean sectionChildChild HealthChild YouthChildren (0-21)Chronologic Fetal MaturityClampingsClinicalClosure by clampCollaborationsComplementComplement ProteinsComplexConduct Clinical TrialsCongenital AbnormalityCongenital Anatomical AbnormalityCongenital DefectsCongenital DeformityCongenital MalformationConsentCritical CareDataData Coordinating CenterData Coordination CenterDevelopmentDiabetes MellitusDysfunctionEnrollmentEnvironmentEquipoiseErythrocyte TransfusionEthnic OriginEthnicityEventEvidence Based MedicineExclusionExposure toFamilyFeasibility StudiesFetal AgeFrequenciesFunctional disorderGeneral PopulationGeneral PublicGestationGestational AgeGoalsGrowth and DevelopmentGrowth and Development functionGuidelinesHealthHealth BenefitHealth Care ProvidersHealth PersonnelHeart CatheterizationHeart Catheterization ProcedureHeart MalformationHeart Surgical ProceduresHematologyHigh-Risk PregnancyHospital AdmissionHospitalizationHospitalsHumanHyperviscosityInfantInfrastructureInsertion of catheter into heart chamberIntensive CareInternationalInterventionInvestigatorsIron deficiency anemiaJointsMeasuresMediatingMissionModern ManMothersMotorMovementNational Institutes of HealthNeonatalNeurologicNeurologic outcomeNeurologicalNeurological outcomeNewborn InfantNewborn resuscitationNewbornsNormal PlacentomaOperative ProceduresOperative Surgical ProceduresOrgan SystemOutcomeParentsParturitionPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPediatricsPerceptionPhysiologicPhysiologicalPhysiopathologyPlacentaPlacenta Embryonic TissuePlacentomePolycythemiaPopulationPost-partum HemorrhagePostpartum HemorrhagePregnancyProcessPublic HealthQuestionnairesRaceRacesRandomizedRandomized, Controlled TrialsRecommendationRecordsRed Blood Cell TransfusionReportingResearch DesignResearch PersonnelResearchersRiskSafetySeveritiesSiteStrokeStudy TypeSubgroupSurgicalSurgical InterventionsSurgical ProcedureSurvey InstrumentSurveysSurvivorsTestingThrombosisTranslatingUmbilical CordUmbilical cord structureUncertaintyUnited States National Institutes of HealthVaginaVulnerable Populationsabnormal heart developmentadherence rateadverse consequenceadverse outcomeagesassess effectivenessbody movementbrain attackcerebral vascular accidentcerebrovascular accidentclinical significanceclinically significantcohortcomplementationcongenital cardiac abnormalitycongenital cardiac anomaliescongenital cardiac diseasecongenital cardiac disordercongenital cardiac malformationcongenital heart abnormalitycongenital heart anomalycongenital heart diseasecongenital heart disordercongenital heart malformationcostcritical congenital heart diseasedesigndesigningdetermine effectivenessdevelopmentaldiabetesdoubteffectiveness assessmenteffectiveness evaluationenrollevaluate effectivenessexamine effectivenessexperiencefetalfetal bloodfetal diagnosishealth care personnelhealth care workerhealth providerhealth workforceheart defectheart surgeryhigh riskimprovedinjury to the myocardiumkidsmaternal hypertensionmaternal outcomematernal riskmedical personnelmortalitymother outcomemultidisciplinarymyocardial injuryneonatal morbidityneonatal resuscitationneonatenewborn childnewborn childrennewborn morbidityparentpathophysiologypatient oriented outcomespostnatalprimary outcomeracialracial backgroundracial originrandomisationrandomizationrandomized control trialrandomized, clinical trialsrandomly assignedrecruitsecondary outcomesexstrokedstrokesstudy designsurgerythrombotic diseasethrombotic disordertreatment providervulnerable groupvulnerable individualvulnerable peopleyoungster
Description preview
PROJECT SUMMARY/ABSTRACT
Clamping and cutting the umbilical cord is the most common intervention in humans, occurring in 140 million
annual births. To maximize expediency (manage 3rd stage of labor, initiate neonatal resuscitation), early cord
clamping (ECC) is performed within ~30 sec of delivery. Recently, evidence has emerged on the health…
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