grant
10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study
Organization UNIVERSITY OF ALABAMA AT BIRMINGHAMLocation BIRMINGHAM, UNITED STATESPosted 4 Mar 2026Deadline 28 Feb 2031
NIHUS FederalResearch GrantFY20260-11 years old10 year old10 years of age11 year old11 years of age2 year old2 years of age21+ years old5 year old5 years of ageACOGActive Follow-upAddressAdjuvant TherapyAdolescentAdolescent YouthAdultAdult HumanAdult-Onset Diabetes MellitusAgeAmerican College of Obstetricians and GynecologistsAmerican College of Obstetricians and GynecologyAmerican College of Obstetrics and GynecologistsAmerican College of Obstetrics and GynecologyBMIBMI percentileBMI z-scoreBeta CellBirth WeightBlackBlack raceBlindedBloodBlood PressureBlood Reticuloendothelial SystemBody mass indexCardiometabolic DiseaseCardiometabolic DisorderCell FunctionCell PhysiologyCell ProcessCells Placenta-TissueCellular FunctionCellular PhysiologyCellular ProcessChildChild HealthChild YouthChildhoodChildhood diabetesChildren (0-21)Chronologic Fetal MaturityCollaborationsContinuous Glucose MonitorD-GlucoseDEXADXADataData Coordinating CenterData Coordination CenterDevelopmentDextroseDiabetes MellitusDiagnosisDimethylbiguanidineDimethylguanylguanidineDrugsDual-Energy X-Ray AbsorptiometryDual-Energy Xray AbsorptiometryDysfunctionEffectivenessEligibilityEligibility DeterminationEnrollmentEnsureEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessExposure toFastingFatsFatty acid glycerol estersFemaleFetal AgeFollow-Up StudiesFoundationsFunctional disorderFutureGestationGestational AgeGlucoseGoalsGovernmentHDL CholesterolHDL Cholesterol LipoproteinsHealthHigh Density Lipoprotein CholesterolHigh PrevalenceHispanicHourHumulin RHyperglycemiaImageIncidenceInsulinInsulin CellInsulin ResistanceInsulin Secreting CellInsuranceKetosis-Resistant Diabetes MellitusKnowledgeLeannessLong-Term EffectsLongitudinal StudiesLongitudinal SurveysLow Birth Weight InfantMaturity-Onset Diabetes MellitusMeasuresMedicalMedicationMetabolic syndromeMetforminMethodologyMuscleMuscle TissueN,N-dimethyl-imidodicarbonimidic diamideNHANESNIDDMNational Health and Nutrition Examination SurveyNeonatalNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusNormal PlacentomaNovolin ROGTTObesityOral Glucose Tolerance TestOutcomeParticipantPersonsPharmaceutical PreparationsPhenotypePhysiopathologyPlacebosPlacentaPlacenta Embryonic TissuePlacentomePopulationPre-DMPrediabetesPrediabetes syndromePrediabetic StatePregnancyPregnancy in DiabetesPregnancy in DiabeticsPregnant WomenProtocol ScreeningQuetelet indexRandomizedRecommendationRegular InsulinResearchResearch SpecimenRiskRisk FactorsSafetySham TreatmentShapesSiteSkinfold ThicknessSlow-Onset Diabetes MellitusSmall for Gestational Age InfantSpecimenStable Diabetes MellitusSubcellular ProcessT2 DMT2DT2DMTest ResultTestingThinnessTimeTransmissionTriacylglycerolTriglyceridesType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesVisitWomanYouthYouth 10-21active followupadiposityadjuvant treatmentadult onset diabetesadult youthadulthoodage 10age 10 yearsage 11age 11 yearsage 2age 2 yearsage 5age 5 yearsaged 2 yearsaged two yearsagesalpha-Lipoprotein Cholesterolcardiometaboliccardiometabolismchild adipositychild obesitychildhood adipositychildhood obesitycohortcontinuous blood glucose monitorcontinuous blood sugar monitorcontinuous glucose measurementcontinuous sugar monitorcorpulencedesigndesigningdevelopmentaldiabetesdiabetes during childhooddiabetes in childhooddiabetes in childrendouble-blind placebo control trialdouble-blind placebo controlled trialdouble-masked controlled trialdrug/agentearly in pregnancyearly pregnanciesearly pregnancyearly stage of pregnancyeleven year oldeleven years of ageenrollepigeneticallyexpectant motherexpectant womenexpecting motherexpecting womenexperiencefastedfasting glucosefastsfive year oldfive years of agefollow upfollow-upfollow-up research studyfollow-up surveyfollowed upfollowupglycemic controlhigh BMIhigh body mass indexhyperglycemicimagingimprovedimproved outcomein uteroindividuals who are pregnantinnovateinnovationinnovativeinsightinsulin resistantinsulin toleranceintergenerationaljuvenilejuvenile humanketosis resistant diabeteskidslong-term studylongitudinal outcome studieslongitudinal research studylow birth weightlow birthweightmalematernal conditionmaturity onset diabetesmortalitymultidisciplinarymuscularneonatal morbidityneonatenewborn morbidityobese childrenobesity during childhoodobesity in childrenoffspringpathophysiologypediatricpediatric diabetespediatric obesitypeople who are pregnantpre-diabetespre-diabeticprediabeticpregnant femalespregnant motherspregnant peoplepregnant populationspreventpreventingprogramsrandomisationrandomizationrandomly assignedsexsham therapyskin fold measurementskin fold thicknessskinfold measurementsmall for gestational agestudy with follow-upten year oldten years of agethose who are pregnanttransmission processtreatment trialtwo year oldtwo years of agetype 2 DMtype II DMtype two diabeteswaist circumferencewomen who are pregnantyoung adultyoung adult ageyoung adulthoodyoungsteryouth ageβ-cellβ-cellsβCell♀♂
Description preview
In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exposure to maternal T2D in pregnancy. The…
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